Mary Elizabeth Hartman (December 23, 1943 – June 10, 1987) was an American actress, best known for her performance in the 1965 film A Patch of Blue, playing a blind girl named Selina D'Arcy, opposite Sidney Poitier, a role for which she was nominated for the Academy Award for Best Actress and the Golden Globe Award. The next year, she appeared in Francis Ford Coppola's You're a Big Boy Now (1966) as Barbara Darling, for which she was nominated for a second Golden Globe Award.

On stage, she was best known for her interpretations of Laura Wingfield in The Glass Menagerie and Emily Webb in Our Town. By the late 1970s, Hartman's career had begun to slow, and she quit acting in 1982 after finishing the voice role of Mrs. Brisby in Don Bluth's animated film The Secret of NIMH (1982). She committed suicide five years later by jumping from her apartment window in Pittsburgh, Pennsylvania.