Katy Mixon (born March 30, 1981) is an American actress. She began her career playing supporting roles in films such as The Quiet (2005), Four Christmases (2008), and State of Play (2009), before landing the female leading role in the HBO comedy series Eastbound & Down (2009–2013).

From 2010 to 2016, Mixon starred as Victoria Flynn, sister to Melissa McCarthy's character, Molly, on the CBS sitcom Mike & Molly. She had dramatic parts in films Take Shelter (2011), Drive Angry (2011), and Hell or High Water (2016), and did voice over work in Minions (2015). In 2016, Mixon began starring as Katie Otto, the lead character in the ABC comedy series American Housewife.