William Moseley may refer to:

• Bill Moseley (born 1951), American film actor and musician
• William Moseley (actor) (born 1987), English actor from The Chronicles of Narnia
• William A. Moseley (1798–1873), U.S. Representative from New York
• William Dunn Moseley (1795–1863), Governor of the U.S. state of Florida
• William G. Moseley (born 1965), geographer at Macalester College
• William Mosley (born 1989), American basketball player
• Bill Moseley (bowls) (born 1945), South African lawn bowls player