Celebrity power couple, Giuliana and Bill Rancic are back and this season they face their toughest challenge yet - Giuliana's breast cancer diagnosis. As they have done with all of life's obstacles, the couple embraces their vow to love each other 'in sickness and in health'. What's more, this season will celebrate the couple's achievements, such as the opening of their restaurant RMP Italian in Chicago, which features many of Mamma DiPandi's, Giuliana's mother's, recipes and forces the couple to look for a new home in Chicago. While their immediate focus is on Giuliana's recovery, their dream of starting a family is also top of mind.